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The randomized, double-blind, placebo-controlled trial evaluated orally administered ivermectin alone (12mg once daily for 5 days), and ivermectin single dose (12mg) in combination with doxycycline (200mg stat doxycycline on day 1 adopted by 100mg 12 hourly for subsequent four days) in contrast with placebo, amongst sixty eight hospitalized patients with Covid-19 in Dhaka. A single dose of a hundred and fifty to 200 µg/kg body weight needs to be taken yearly to be effective. Mutation screening was carried out when the primary dose of the analysis drug ivermectin was given, ivermectin therapy was not continued in patients with mutations detected because of genetic examination and these patients had been excluded from the study. Critically, temporary negative effects of a successful treatment may be thought of as a negative final result, which could end in falsely concluding that the treatment is not effective. The aspect impact information reported in this trial raises major issues, with more negative effects reported in the placebo arm, suggesting that extra placebo patients might have received therapy. Unlike earlier therapies, which had serious - generally fatal - uncomfortable side effects, ivermectin is safe and can be utilized on a large scale.

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